Niacin-Infographic-High-Res (1)

What Happens When You Take Niacin?

20 – 30 mins – Your blood vessels dilates, a warming sensation spreads across your body, you start to itch and your face flushes. This is known as the ‘niacin flush’, a sign it is working its magic.

30 mins – 1hr – You have this warm glowing sensation that can last for several hours. A bit like the ‘runner’s high’ you get after a gym workout.

Your mood elevates, energy goes up and your brain functions better with more clarity.

1hr+ There are many long term benefits associated with Niacin:

  1. Detox: Combination of niacin, exercise and sauna is a powerful way to detox your body from heavy metals and toxins stored in fat cells.
  2. Energy: Niacin is essential in the production of energy in the body. Deficiency causes tiredness and fatigue. 50 – 500 mg daily will give a natural energy boost.
  3. Arthritis: Studies confirm niacin is better than NSAIDS for arthritis. Moderate arthritis 1,000 to 1,500 mg a day. In more severe cases, as much as 3,000 mg to 4,000 mg have been recommended.
  4. Cholesterol, Triglycerides + Reversing Heart Disease: Recommended 1,000 to 3,000 mg of niacin a day.Niacin lowers cholesterol more effectively than statins in various studies and also lowers triglycerides. It reduces the blood fats called “very low density lipoproteins,” which have been linked to heart disease and cancer. It improves the blood sugar problems that can lead to damage of the arterial walls. It dilates blood vessels, which improves the circulation to areas starved of oxygen and nutrients.
  5. Memory loss: 1,000 mg of niacin taken 3 times a day can improve memory, and correct some senility problems.
  6. Prevents Hair Loss + Balding: Increases blood flow to scalp, important in hair growth and reduces production of DHT linked to balding.
  7. Insomnia: Niacinamide activates benzodiazepine receptors in the brain, which affects sleep. Dosages of 50 mg to 500mg of niacin that is converted into niacinamide in the body taken at bedtime have helped many people sleep better.
  8. Severe Depression & Schizophrenia: The usual dose range is 3,000 to 9,000 milligrams daily divided into three doses, but occasionally some patients may need more.
  9. Cancer: Has the potential to influence DNA repair, genomic stability, and the immune system, eventually having an impact on cancer risk, as well as the side effects of chemotherapy in the cancer patient.
  10. Acne: Many reports show Niacin can get rid of acne at daily doses of 400/500 mg.
  11. Alzheimers: Studies have shown that vitamin B3 niacin can help protect against Alzheimer’s disease and other age related brain disorders that result in cognitive decline.

Important Points:

When you first take Niacin, you will most likely get an alarming flushing effect. Do not worry about this, it is just a sign of Niacin working its magic. The flush is due to niacin  that is chemically nicotinic acid creating a dilating effect on your blood vessels.

Try my favorite source of niacin here.

Niacin – The Most Powerful Detox Agent?

L Ron Hubbard was a big advocate of Niacin (Vitamin B3) supplementation during sauna use to enhance the detoxification process. A starting dose of 100mg is ramped up to 1000 – 5000mg towards the end of the program,

In more recent times Dr David Roo and Dr George Yu have used niacin and saunas to help detox war veterans from Agent Orange toxicity and 9/11 fighters from toxic debris.

The way niacin works is by mobilizing fat cells to release toxins into the blood where they can be removed by the body. A dose of around 100mg may cause in most people an effect known as the ‘niacin flush’.

This happens because certain doses of niacin causes your blood vessels to dilate and creates a sensation of warmth. This is a sign the detoxification effect of niacin is at its peak and will be most effective. At higher doses however the flushing effects will actually fade away.

NMN or nicotinamide mononucleotide a precursor to NAD+ that stimulates DNA repair in cells, can mimic the restorative effects of exercise, rejuvenating muscle tissue and other cells. Read more about this here.

The Renegade Pharmacist’s Personal Experience With Niacin

I have to admit I have become a niacinaholic. I love the stuff. Not everyone can handle the flush, but I absolutely love it. The first time I took it, it was a sudden shock to my system and I freaked out a little bit, as do most people.

But after the intense heat faded, a glowing sensation radiated from my body. I had a clear mind, full of energy and felt warm and fuzzy for the next few hours. The next day I followed a sauna detox ritual that I now do religiously.

This is when I realized the true power of niacin. Everything got enhanced. My meditation, my level of clarity, and my level of clarity after the experience.

Niacin is my new best friend. I was compelled to read as much as I could about this miraculous vitamin, and the studies were eye opening.

What concerned me was the fact that there was not a single mention of this extraordinary vitamin during my 4 years training as a pharmacist.

Then when I qualified, I never heard of niacin’s benefits till very recently. After a couple of months of taking niacin regulary I went to get a hair cut.

My favorite hairdresser noticed that my hair had grown back a bit on the back of my head that had been thinning quite a lot over the last few years. I was gobsmacked. I then discovered many high end hair loss treatment centres also use niacin as part of their treatment plan.

I have since recommended niacin to various friends and family and all have reported benefits from taking it too and several have started to take it regularly like I do.

Niacin made me once again believe in the power of high doses of certain vitamins, and perhaps they are not just expensive urine, but something the body craves because our diet has become depleted over many years of mass farming and agriculture.

If you want a good niacin capsule so you can start feeling the effects right away, try the one that I use on a daily basis:

Buy quality Niacin here.



By |2019-03-22T01:25:31+00:00January 14th, 2017|Health, Therapeutic|52 Comments

About the Author:

The Renegade Pharmacist
I am an ex-community pharmacist turned 'renegade' after recovering from a chronic illness without medication, when conventional medicine had given up hope. This site will share what has worked for me and the latest research in holistic healthcare.


  1. Owen Doonan January 18, 2017 at 6:12 am - Reply

    Hi Niraj, it has been quite a while since we caught up, How do you deal with the quick flush issue. that Niagen has solved with a pricy alternative that is well documented on Amazon. I have been using it for 9 months and it works but is pricey at $50 usd for a months supply. IMHO it could work to stem or reverse the effects of Alzheimer’s. via telomere length extension! renewal.

    All the best,

  2. Colleen Foster January 18, 2017 at 8:10 pm - Reply

    Hi Niraj Naik thanks for this awesome article. If one buys Niacin how does one find a product that actually causes the flush. I have read that most products are the sort that do not induce a flush? Thank you.

  3. Jo April 30, 2017 at 3:32 pm - Reply

    Thank you for this. I love the fact that you are someone who used to “buy into the system” through your vocation, and then discovered that it was BS. So happy for you that you healed yourself and now generously share your wisdom with us. I am a big proponent of not giving your health away to BigPharma and BigMedicine. Whole foods, intermittent fasting, adequate sleep, supplements, meditation and engaging in activities you love I believe have more power to keep you happy and healthy over any medication. Keep up the good work, and thank you! 🙂

    • Susan L Wilson September 13, 2017 at 5:46 am - Reply

      Totally agree ~ kudos!

  4. Kathlee Hammon July 13, 2017 at 5:32 pm - Reply

    my doctor started me on 500mg. of niacin because my triglycerides were dangerously high- my triglycerides went down from almost 400 to 70!I also noticed my hair quit falling out as much. I take it at night with a baby aspirin and a small amount of food-(spoonful of peanut butter) and I haven’t been bothered by the flushing at all. Sometimes my skin would itch a little but not bad. all in all I think niacin is a winner!

  5. Paul Collins July 25, 2017 at 5:18 pm - Reply

    Have been taking 1000mg to 2000mg Of Niacin for high cholesterol as I have a genetic abnormality that causes problems,

    30% increase in hdl cholesterol triglycerides are down resting heart rate is down

    It’s a wonder vitamin !

  6. Peter September 6, 2017 at 5:28 pm - Reply

    Thanks! I have takimg niacin daily for about 6 months now but in low doses. 1 tab in morning and 1 at night (Solal Niacin)
    What is your feeling on Kevin Trudeau’s book: Natural Cures “They” Don’t Want You
    to Know About? I recently got hold of a copy and plan to read through it. Thx

  7. David September 7, 2017 at 2:06 am - Reply

    Thank you for your insight.I have noticed the niacin flush too.I am looking into taking this with other supliments to see how well they work together.

  8. Sabine Cudjo September 20, 2017 at 2:27 am - Reply

    Thank you for this great information, I never realized that niacin has that many benefits.

  9. Sameer October 2, 2017 at 10:00 pm - Reply

    Is niacin effective for better performance in bed and for hard erections?

    • The Renegade Pharmacist
      The Renegade Pharmacist December 29, 2017 at 9:03 am - Reply

      It may help as it dilates blood vessels and improves circulation, however I have no direct experience with that!

    • J. Hub March 3, 2018 at 6:30 am - Reply

      No, I took 2000 mg a day for several months and it didn’t help in that area at all.

  10. vera November 14, 2017 at 7:18 pm - Reply

    My LDL is high and Triglycerides also, overall my cholesterol is high in the 300’s. i am so thinking of taking niacin tablets . Statins cause me muscle pain so that is out. what dosage would you recommend?

    • The Renegade Pharmacist
      The Renegade Pharmacist December 29, 2017 at 9:00 am - Reply

      Please read the article, all the info is there: Cholesterol, Triglycerides + Reversing Heart Disease: Recommended 1,000 to 3,000 mg of niacin a day.Niacin lowers cholesterol more effectively than statins in various studies and also lowers triglycerides. It reduces the blood fats called “very low density lipoproteins,” which have been linked to heart disease and cancer. It improves the blood sugar problems that can lead to damage of the arterial walls. It dilates blood vessels, which improves the circulation to areas starved of oxygen and nutrients.

  11. Charlie November 21, 2017 at 6:44 am - Reply

    So many things are a coumadin conflict, it may be feasible, with caution, to take a second blood thinner by adding a counterbalancing agent like COQ10 or K-2.

  12. Paul Norton November 22, 2017 at 4:12 pm - Reply

    Yes Whole Foods but not from Wholefoods market store ,They are scammers ,Whole foods means grow your own or farmers market,Not a greedy corporation who does not know in reality where their crap comes from.17 year employee

  13. Samantha December 2, 2017 at 10:57 am - Reply

    It is completely irresponsible to suggest that people take such high amounts of a vitamin that is actually only needed in such small amounts. 30mg is the highest amount anyone should take without doctor supervision. Self medicating high amounts can lead to liver toxicity and a host of other problems. Also referencing L Ron Hubbard on anything slightly scientific is like referencing OJ Simpson in an article on happy marriages. A complete quack article.

    • The Renegade Pharmacist
      The Renegade Pharmacist December 29, 2017 at 8:51 am - Reply

      Please do the research on niacin before making such bold and negative claims. There are absolutely no risks of liver toxicity with pure vitamin b3, the only problems occur if you take the sustained release niacin, which I explain in the article, it has also been used as a detox agent by many respected doctors and clinics around the world. Read up on Dr. Andrew Saul’s new book, Niacin: The Real Story is co-written with Abram Hoffer M.D., Ph.D

  14. Melba J Robinson Gray December 3, 2017 at 1:06 pm - Reply

    Thank you so much. Please don’t give up.

  15. Paul December 29, 2017 at 1:44 pm - Reply

    Excellent. I’ve been taking 100 mgs a night with melatonin and valerian capsules as a bed time regimen… far so good. What is interesting is I will sometimes get ‘the flush’ and other times barely notice one. Ive not felt a need to up the dose as of yet….seems like a good maintenance dose for me. Thanks!

  16. Mena December 31, 2017 at 5:57 pm - Reply

    I am using Niacinamide for my son. 3 g divided in 3 times per day. It has a calming effect. What is your opinion of Niacinamide vs niacin?

    • The Renegade Pharmacist
      The Renegade Pharmacist July 22, 2018 at 9:52 am - Reply

      Pure niacin that gives you the flush is the best for therapeutic effects

  17. sandra elliott January 22, 2018 at 4:10 am - Reply

    use it great cholesterol now normal with more energy I’m 77
    Dr had me on cholestrol pills 15 yrs
    till brother said try niacin
    try it don’t mind the hot flush very cheap at costco
    take 500m 3 times a week

    i buy 500 mg 500 tablets

  18. Alex February 26, 2018 at 8:28 am - Reply

    Hello! Anyone used Niacin to treat depression? Any feedback would me much appreciated. Thanks!

  19. Lisa Lambert May 29, 2018 at 12:17 am - Reply

    Thank you for the article! Can you take niacin while taking levothyroxine?

    • The Renegade Pharmacist
      The Renegade Pharmacist July 22, 2018 at 9:51 am - Reply

      Yes, but always check with your doctor first.

    • Kathy Coleman January 10, 2019 at 6:17 am - Reply

      You won’t have to take your Levothyroxine if you take niacin!

  20. James June 9, 2018 at 2:39 pm - Reply

    I am suffering from sleep over 37 years have tried everror now on have started taking 500 mg x 2 tabs everyday will this help pla

    • The Renegade Pharmacist
      The Renegade Pharmacist July 22, 2018 at 9:50 am - Reply

      Test it and see how you feel.

  21. Michelle June 12, 2018 at 6:16 pm - Reply

    I have high cholesterol and triglycerides. I just tried my first dose of Niacin from NOW. I opened the 500 mg capsule and took a little for my first dose. Right away I felt the flush!!! On may face and strangely on my rear end cheecks! How embarrassing ?. I was glad to read your above report. Thank you for this!!
    May we all be blessed with health

  22. Julie Harrington June 22, 2018 at 11:58 pm - Reply

    For years,I have been taking 500 mg. of Niacin daily for high cholesterol. Recently my physician said that there is new evidence that it is detrimental to the heart, rather than being helpful. When I asked her who did the research (Was itt the company who produces Lipitor?) she did not know and asked me to do that research for myself. I haven’t been able to find anything. Does anyone know of this research and who produced it? Where can I find information on time release niacin. I cannot locate your article. Thanks.

    • The Renegade Pharmacist
      The Renegade Pharmacist July 22, 2018 at 9:49 am - Reply

      I have not read that before. The form of niacin if sustained release can be harmful to the liver. You should take only full flush niacin.

    • Kay Carter August 22, 2018 at 7:56 pm - Reply

      Wow… she left it without producing facts… No creditability…

  23. Audrey June 30, 2018 at 4:03 am - Reply

    Agreed. The person reporting information is just the person reporting information. Facts are facts.

  24. Laura July 16, 2018 at 10:49 pm - Reply

    What is the problem using sustained release naicin?

    • The Renegade Pharmacist
      The Renegade Pharmacist July 22, 2018 at 9:50 am - Reply

      It can affect liver function.

  25. Mily August 20, 2018 at 12:03 pm - Reply

    Hi pharmacist. That’s great sharing about naicin. I haven’t known before. i wonder if it is similar to multi-vitamin. Nowadays, it seems trendy to stay fit and healthy. My brother is one of who love taking supplement such multi-vitamin as shown here i found that he got a good result. By the way, I’m also interested in Naicin, I’m learning more about its benefits. Thank you very much for your sharing.

  26. Cynthia Baker August 20, 2018 at 10:24 pm - Reply

    If taking niacin at any dose 100mg or even working up to 1000mg B3 daily, do you feel the need to take binders? Like charcoal or Bentonyte Clay.
    My husband would be taking it for high cholesterol and triglycerides and somewhat elevated sugar. I would be taking it to remove toxins in general and help with memory issues.
    I’m familiar with Ron Hubbards protocol- but I am not interested in doing that full protocol.
    Thank you.

  27. Jenn August 22, 2018 at 1:48 am - Reply

    I want to begin using niacin, but I think I am confused by the detox portion. Does niacin detox the system every time it is used where I would need to do the sauna and charcoal step in order to absorb all of the released toxins? Or is it still safe to take niacin on a daily basis without the charcoal?

  28. valarie August 27, 2018 at 7:04 am - Reply

    Hi,I take 100mg a day,is that good enough,?I get the flush,when i stop getting the flush can I or should I increase my dosage please ?

  29. Krishna September 29, 2018 at 11:37 am - Reply

    Can you suggest where can I get Niacin full flush in India? On Amazon it is everything flush free or no flush. Can you tell company in India who manufactures niacin full flush?

  30. baldev September 30, 2018 at 1:35 pm - Reply

    I have no word to explane yourheart is great open so big and pious pure and your mind You have a sprit that can sustain the whole world other people problem. full of virtuies you do not need blessing you are blessed so much that world can sustain in you

  31. Sandra Randall October 8, 2018 at 6:56 pm - Reply

    Is there any medication or supplements that shouldn’t be taken with Niacin

  32. Toli October 18, 2018 at 12:14 am - Reply

    thank you for this article, I have a question: do you know if the no-flush type niacin has the same effects as regular type? I suppose the flushes are important for the detoxification effect?

  33. Dr Sam October 18, 2018 at 10:27 am - Reply

    Is it right to use niacin while on regular anti hypertensive?

  34. Bryan Henke October 22, 2018 at 10:49 pm - Reply

    Many top lipid doctors say that it causes insulin resistance and although in theory can lower APO B, in actuality it doesn’t. There are studies on cholesterol that showed anything statistically significant except the negative effects of it at such high doses. See Tom Dayspring for more on this. Can be very dangerous to suggest these therapeutic benefits without the research. Research is not statistically significant to prove any of these claims you made

  35. Ronel Dreyer November 7, 2018 at 3:23 pm - Reply

    Using it about 2000 mg every night, love the flush and all the benefits! My husband’s cholesterol came down from 6,8 to 4,6 and sleeps well, hair growth and skin improved dramatically. My son 11, takes 4x daily, helps with immunity, ADD, better sleep, more focus and concentration (together with vit C, zinc, magnesium glycinate, Brahmi)👌🏼

  36. Carney November 12, 2018 at 12:00 am - Reply

    Want to try niacin to help manage high blood pressure, but I take Uloric for gout and read niacin will aggravate gout. Your thoughts? I hate BP meds and the way they mess up the endocrine system. Thank you.

  37. Lynn Vasquez November 15, 2018 at 1:15 pm - Reply

    The flush is uncomfortable for me as well, but if you start with a low dose and work your way up over time, the flush gets much more tolerable. I start with one 100 mg tablet and add one additional tablet to my morning routine each time the flush becomes barely noticeable. If I run out or don’t take it for a while for some reason, I have to start at a lower dose and work my way up again.

  38. Andrew November 26, 2018 at 9:17 pm - Reply

    Is there an optimal time of day to take niacin? I’m 39, cholesterol just slightly high and trying to improve that as well as energy levels. Would I be better off taking 500 mg 2 x daily, or all in one dose? Also, is it better to take daily or every other day, etc?

  39. Lee January 1, 2019 at 8:41 pm - Reply

    I take 500 mg. of Niacin 3 times daily after each meal. You’ll get much more of a flush if you take it on an empty stomach. The reason more people don’t take Niacin is that they can’t get through the flush the first few times. It’s pretty bad at first—you feel like you’re burning up and itching all over like crazy! But if you stay with it for about 3 weeks–you start getting addicted to that flush & enjoying it! The itching pretty much stops. I know that sounds strange when it feels so uncomfortable at first, but it’s true, and I notice others who use it regularly have mentioned it. I love the flush feeling now. I will never stop taking it. One thing I noticed since I started taking it is I never gain weight–no matter what I eat! I spent December pigging out on all kinds of cake & pies & candy during the holidays—no exercise, and I actually lost 1 lb! It really doesn’t make you lose weight, but if you can diet & get to the weight you want to be–it’ll keep you from gaining it again! Not sure why, but it has worked that way for me ever since I started it. I started taking it to bring cholesterol levels down, and it has worked for that, too!

  40. Alex January 14, 2019 at 11:46 pm - Reply

    Thanks for this excellent and well organized post! Niacin is wonderful.
    For the skepticals… read, study, do your own research. Stop taking toxic pills and focus on nutrients, good nutrition and healthy life style, there are not magic pills.

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